1. Analyze the following pedigree and state the most likely inheritance pattern, your reason for the choice and an example of the disease/condition.

Pattern of Inheritance

Rationale

Example

2. Analyze the following pedigree and state the most likely inheritance pattern, your reason for the choice and an example of the disease/condition.

Pattern of Inheritance

Rationale

Example

3. Analyze the following pedigree and state the most likely inheritance pattern, your reason for the choice and an example of the disease/condition.

Pattern of Inheritance

Rationale

Example

Use a T or F to show whether this statement is true or false.

4. If there are no other affected family members, it is safe to assume that the condition is not genetic.

1. X-linked

Only males are affected, inherited through their mothers

Hemophilia, Duchenne muscular dystrophy

2. Autosomal recessive

Horizontal pattern of inheritance, parents are second cousins

PKU, sickle cell anemia

3. Multifactorial

Multiple affected family members

Neural tube defect, pyloric stenosis, cleft lip/palate

4. False Isolated abnormalities may be the result of a new mutation, nontraditional pattern of inheritance or autosomal recessive single gene disorders.

Lesson 2-Table of Contents) (Next) (Glossary)